Progesterone

Clinical definition of the progesterone test
Progesterone is a hormone produced mainly in the ovaries. It plays a vital role in pregnancy. It makes the uterus ready for implantation of a fertilized egg. Progesterone levels rise and fall on a monthly basis. Levels elevate when the egg is released from the ovary and continue to rise with early pregnancy or fall to initiate menstruation. Abnormal levels of progesterone are seen in ectopic pregnancy and irregular or no menstrual periods
Increased progesterone levels also are seen in:

  • Ovarian cysts
  • Non-viable pregnancies known as molar pregnancies
  • Ovarian Cancer
  • Overproduction of progesterone by the adrenal glands
  • Congenital adrenal hyperplasia (CAH)

Low levels of progesterone are associated with:

  • ToxemiaDecreased function of ovaries
  • Lack of menstruation (amenorrhea)
  • Menopause
  • Abnormal pregnancy (dying pregnancy/unhealthy pregnancy)

Why is the progesterone test done?
Serum progesterone test measures the level of progesterone in the blood. It is done to diagnose or rule out disorders associated with abnormal progesterone levels, usually related to infertility or recurrent miscarriage, an ectopic or failing pregnancy, abnormal uterine bleeding and to monitor   the health of a pregnancy and track ovulation.

What are the common signs/symptoms when the progesterone test is done?

  • Irregularity of the menstrual cycle,
  • Strong cramps during menstruation,
  • Higher incidence of PMS
  • Greater presence of blood clots during periods.
  • Infertility  
  • Fatigue
  • Dry Skin
  • Insomnia
  • Depression
  • Dysfunction of the thyroid gland
  • Hypothyroidism
  • Back-ache – particularly pre-menstrual back ache
  • Miscarriages(BOH—Bad obstetric history)
  • Weight gain
  • Pre-menopausal bone loss,
  • Memory loss or lack of mental acuity

What should I do before the progesterone test?

Specimen type

Specimen collection procedure

Preparatory instructions before the test *

Serum (Blood Sample)

Venipuncture

Collection of blood from a vein, usually from the arm.

  • The patient's last menstrual period and trimester of pregnancy should be noted.
  • No Fasting Required.
  • No other special preparations required.

* Subjects suffering from any illness or on oral or injectable medications are advised to consult their physician prior to requesting any tests or procedures.

How do I interpret my progesterone test results?

GENDER

Reference Range *

FEMALE

 

Menstrual cycle

Mid-follicular phase

upto 0.98 ng/ml

Follicular phase

up to 1.13 ng/ml

Luteal phase

 

1.2 to 15.9 ng/ml

 

Post menopausal

Below 0.2 ng/ml

 

Pregnancy:-

First trimester

2.8 to 147.3 ng/ml

Second trimester

22.5 to 95.3 ng/ml

Third trimester

27.9 to 242.5 ng/ml

 

Children- Age

Boy (ng/ml)

Girl (ng/ml)

8-15 days

0.35-2.3

0.35-1.42

1-3 years

0.0-0.61

0.0 -0.61

4-6 years

0.0-1.9

0.0-0.99

7-8 years

0.26-1.07

0.25-0.99

9-10 yrs

0.0-1.06

0.13-1.00

11 yrs

0.32-1.05

0.37-0.92

12 yrs

0.32-1.53

0.49-1.68

13 yrs

0.41-1.46

0.4-1.46

14 yrs

0.39-1.24

0.56-12.3

15 yrs

0.64-2.5

0.7-13.4

17 yrs

0.82-1.9

0.77-11.3

18 yrs

1.2-3.0

1.27-13.0

‘*A Reference range is a set of values which helps the healthcare professional to interpret a medical test. It may vary with age, gender, and other factors. Reference ranges may also vary between labs, in value & units depending on instruments used and method of establishment of reference ranges’

Diseases/conditions related to the progesterone test

  • Amenorrhea
  • Ovarian Cancer
  • Toxemia
  • Congenital adrenal hyperplasia (CAH)

Other tests related to the progesterone test

  •  Estrogens
  •  hCG
  •  FSH
  •  LH
  • TSH

 


Synonyms : Pregnanediol
Book This Test
Progesterone

Book Related Tests
  • FSH, LH, Prolactin
  • LH (Luteinizing hormone)
  • FSH (Follicle Stimulating Hormone)

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