SGPT / ALT (Alanine transaminase)

Clinical definition of the Alanine transaminase (SGPT) test
Alanine aminotransferase (ALT) is an enzyme found mostly in the cells of the liver and kidney; much smaller amounts of it are also found in the heart and muscles. ALT is measured to see if the liver is damaged or diseased.  In healthy individuals, ALT levels in the blood are low. When the liver is damaged, ALT is released into the blood stream, which results in high ALT levels.

Why is the Alanine transaminase (SGPT) test done?
The alanine aminotransferase (ALT) test is done to:

  • Identify liver disease, especially cirrhosis and hepatitis caused by alcohol, drugs, or viruses
  • Help check for liver damage
  • Find out whether jaundice was caused by a blood disorder or liver disease
  • Keep track of the effects of cholesterol-lowering medicines and other medicines that can damage the liver

ALT is also carried out, either by itself or with other tests, for people who are at an increased risk for liver disease. Some examples include:

  • Persons who have a history of known or possible exposure to hepatitis viruses
  • Those who are heavy drinkers
  • Individuals whose families have a history of liver disease
  • Persons who take drugs that might occasionally damage the liver
  • Persons who are overweight and/or have diabetes

What are the common signs/symptoms when the Alanine transaminase (SGPT) test is done?

  • Weakness
  •  Fatigue
  • Loss of appetite
  • Nausea, vomiting
  • Abdominal swelling and/or pain
  • Jaundice
  • Dark urine, light colored stool
  • Itching (pruritus)

What should I do before the Alanine transaminase (SGPT)  test?

Specimen type

Specimen collection procedure

Preparatory instructions before the test *

Serum

(Blood Sample)

Venipuncture

(Collection of blood from a vein, usually from the arm)

No Fasting Required.

No other special preparations required.

*Subjects suffering from any illness or on oral or injectable medications are advised to consult their physician prior to requesting any tests or procedures.

How do I interpret my Alanine transaminase (SGPT) test results?

Reference Range*

Interpretation

Female

30 to 65 U/L

Male

30 to 65 U/L

Children

Male

Female

1 - 7 days

20 - 54 U/l

21 - 54 U/l

8 - 30 days

24 - 54 U/l

22 - 46 U/l

1 - 3 months

27 - 54 U/l

26 - 61 U/l

4 - 6 months

26 - 55 U/l

26 - 51 U/l

7 - 12 months

26 - 59 U/l

26 - 55 U/l

1 - 3 yrs.

19 - 59 U/l

24 - 59 U/l

4 - 6 yrs

-

24 - 49 U/l

10 - 11 yrs.

-

24 - 44 U/l

4 - 11 yrs

24 - 49 U/l

-

12 - 13 yrs

24 - 68 U/l

24 - 44 U/l

14 - 15 yrs. 

24 - 59 U/l

19 - 44 U/l

16 - 19 yrs

24 - 54 U/l

19 - 49 U/l

‘*A Reference range is a set of values which helps the healthcare professional to interpret a medical test. It may vary with age, gender, and other factors. Reference ranges may also vary between labs, in value & units depending on instruments used and method of establishment of reference ranges’

Diseases/conditions related to the Alanine transaminase (SGPT) test

  • Hepatitis
  • Cirrohosis
  • Ischemia
  • Tumor of liver
  • Ischemia  
  • Viral hepatitis
  •  Infectious Mononucleosis, or myopathy.
  • Congestive Heart Failure
  • Liver damage
  • Bile Duct problem

Other tests related to the Alanine transaminase (SGPT) test

  • AST
  • ALP
  • GGT
  • Bilirubin
  • Liver panel
  • Albumin
  • Total Protein

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SGPT (ALT)

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