Rh Antibody Titer

Clinical definition of the Rh Antibody Titer test
The Rhesus factor is important during pregnancy and causes problems when an Rh–negative person's blood comes in contact with Rh–positive blood. In such cases the Rh Antibody Titre test may be used. To protect against Rh sensitization, all pregnant women should have a blood test at an early stage of pregnancy.

Why is the Rh Antibody Titer test done?
Rh antibody titer test determines the type and quantity of antibodies in the blood. Rh antibodies are likely to rise during pregnancy. Depending on the level of other antibodies these antibodies could cause hemolytic problems in the baby and need to be monitored. It is usually repeated several times during pregnancy (at 32, 36, & 38 weeks). A low titer (less than 1:16) may not pose any problem for the baby. In any test higher than 1:64, an intrauterine exchange transfusion may be suggested.

Who should do the Rh Antibody Titer test (Target population)?
Persons having a blood transfusion or as a screening to check the blood type of a pregnant woman.

What should I do before the Rh Antibody Titer test?

Specimen type

Specimen collection procedure

Preparatory instructions before the test *

Serum (Blood Sample)

Venipuncture - Collection of blood from a vein, usually from the arm.

No Fasting Required.

No other special preparations required.

*Subjects suffering from any illness or on oral or injectable medications are advised to consult their physician prior to requesting any tests or procedures.

How do I interpret my Rh Antibody Titer test results?

Reference Range*

Interpretation

+

Rh Positive

-

Rh Negative

‘*A Reference range is a set of values which helps the healthcare professional to interpret a medical test. It may vary with age, gender, and other factors. Reference ranges may also vary between labs, in value & units depending on instruments used and method of establishment of reference ranges’

Diseases/conditions related to the Rh Antibody Titer test

  • Hemolytic disease of the newborn (HDN)
  • Erythroblastosis fetalis

Other tests related to the Rh Antibody Titer test

  • Coombs Test
  • Blood Group
  • Compatibility testing
  • Crossmatch
  • Antibody identification
  • HLA testing

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Blood Group and Rh Typing

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