Brucella antibody titer

Clinical definition of the Brucella test
Brucellosis, caused by species of the bacteria Brucella is a highly contagious disease, which affects animals including goats, sheep, camels, pigs, elk, deer, cattle and dogs. It is caused by the ingestion of unsterilized milk, cheese or meat from infected animals; close contact with their secretions; from human to human through sexual contact or from mother to child.
It is frequently seen that people working in jobs requiring frequent contact with animals or meat such as slaughterhouse workers, farmers, and veterinarians are at a higher risk.

Why is the Brucella test done?
The test for brucellosis is used to check for antibodies against the bacteria Brucella for a suspected case of the disease.

What are the common signs/symptoms when the Brucella test is done?
Brucellosis begins with mild flu-like symptoms or symptoms such as:

  • Profuse Sweating
  • Severe joint and muscle pain.
  • Inconstant Undulant fevers (up and down in fever)
  • Weakness
  • Anemia
  • Headaches
  • Depression 
  • Abdominal pain
  • Back pain
  • Chills
  • Fatigue
  • Loss of appetite
  • Weight loss
  • Swollen glands

Who should do the Brucella test (Target population)?
Persons who are at high risk of contracting the disease due to close contact with animals and those showing the above signs & symptoms.

What should I do before the Brucella test?

Specimen type

Specimen collection procedure

Preparatory instructions before the test *

Serum (Blood Sample)

Venipuncture - Collection of blood from a vein, usually from the arm.

No Fasting Required.

No other special preparations required.

*Subjects suffering from any illness or on oral or injectable medications are advised to consult their physician prior to requesting any tests or procedures.

How do I interpret my Brucella test results?

IgG

IgM

Reference Range*

Interpretation

Reference Range*

Interpretation

0 to 9 Index

Negative range

0 to 9 Index Reactive

Negative

Above 11 Index

Positive

Above 11 Index

Positive

9 to 11 Index

Borderline

9 to 11 Index

Borderline

Inference: If the test detects antibodies, there is a likeliness of brucellosis infection.
‘*A Reference range is a set of values which helps the healthcare professional to interpret a medical test. It may vary with age, gender, and other factors. Reference ranges may also vary between labs, in value & units depending on instruments used and method of establishment of reference ranges’

Diseases/conditions related to the Brucella test

  • Bone and joint lesions
  • Chronic fatigue syndrome
  • Encephalitis
  • Infective endocarditis
  • Meningitis

Other tests related to the Brucella test

  • Urine culture & sensitivity
  • Blood culture
  • CSF culture
  • Bone marrow culture
  • Serology detecting brucellosis antigen
  • Quantitative immunoglobulins (nephelometry)
  • Serum immunoelectrophoresis
  • Febrile/cold agglutinins

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