Uric Acid

Clinical definition of the Uric acid test
Uric acid is a chemical created when the body breaks down substances called purines. Purines are found in foods and drinks such as liver, mackerel, dried beans and peas, beer, wine. Purines are also a part of normal body substances such as DNA. Uric acid dissolves in blood and is removed from the body by the kidneys and is excreted in the urine; the remainder is eliminated in the stool. If too much uric acid is produced or not enough is excreted, it accumulates in the body causing high levels of uric acid in the blood (hyperuricemia). The presence of excess uric acid causes gout, a condition characterized by inflammation that occurs in joints when crystals derived from uric acid form in the joint (synovial fluid). Excess uric acid also leads to kidney disease.

Why is the Uric acid test done?
The uric acid blood test is carried out to determine the levels of uric acid in the blood and monitor these levels in people undergoing chemotherapy or radiation treatment. This test is used to diagnose gout and the cause of recurrent kidney stones.

What are the common signs/symptoms when the Uric acid test is done?

  • Severe joint pain
  • Redness, swelling, tenderness, inflammation and unbearable pain in the affected joint
  • Peeling of the skin around the affected joint
  • Fever
  • Pain in the back, side, abdomen, groin or genitals
  • Painful and frequent urination
  • Blood In Urine
  • Lethargy
  • Weakness
  • Shortness of breath
  • Generalized swelling
  • Nausea
  • Vomiting
  • Stomach cramps
  • Bleeding
  • Stomach ulcers
  • Diarrhea 

What should I do before the Uric acid test?

Specimen type

Specimen collection procedure

Preparatory instructions before the test *

Serum

(Blood sample)

Venipuncture 

(Collection of blood from a vein, usually from the arm)

No Fasting Required.

No other special preparations required.

Urine

24-hour urine sample-Care must be taken to clean the genitals well before collection.

Follow these steps to get the sample

Day 1- The first morning urine sample on Day 1 must not be collected i.e. bladder must be emptied for the first time.

Note down the exact time of discarding the 1st urine sample.

All urine for the next 24 hours should be collected in the special container provided.

Day 2- collect the first morning urine of Day 2 into the same container, at the same time or within 10 minutes as that noted on the morning of Day 1.

Cap the container. Keep it in the refrigerator or a cool place during the collection period.

No special preparations required.

* Subjects suffering from any illness or on oral or injectable medications are advised to consult their physician prior to requesting any tests or procedures.

How do I interpret my Uric acid test results?  

Gender

Reference Range*

SERUM

Adult Female

2.6 to 6.0 mg/dL

Adult Male

3.5 to 7.2 mg/dL

Children

MALE

FEMALE

1 – 30 days

1.2 – 4.9 mg/dl

1.3 – 6.2 mg/dl

1 – 3 months

1.3 – 5.3 mg/dl

1.3 – 5.8 mg/dl

4 – 6 months

1.4 – 6.4 mg/dl

1.3 – 6.2 mg/dl

7 – 12 months

1.4 – 6.7 mg/dl

1.4 – 6.2 mg/dl

1 – 3 yrs

1.7 – 5.0 mg/dl

1.7 – 5.0 mg/dl

4 – 6 yrs

2.2 – 4.7 mg/dl

2.2 – 4.7 mg/dl

7 – 9 yrs

1.9 – 5.0 mg/dl

1.9 – 5.0 mg/dl

10 – 11 yrs

2.3 – 5.4 mg/dl

3.0 – 4.7 mg/dl

12 – 13 yrs

2.7 – 6.8 mg/dl

3.0 – 5.8 mg/dl

14 – 15 yrs

2.4 – 7.9 mg/dl

3.0 – 5.8 mg/dl

16 – 19 yrs

4.0 – 8.7 mg/dl

3.0 – 5.9 mg/dl

24h Urine sample

Male

250-800mg/24hrs

Female

250-750mg/24hrs

*A Reference range is a set of values which helps the healthcare professional to interpret a medical test. It may vary with age, gender, and other factors. Reference ranges may also vary between labs, in value & units depending on instruments used and method of establishment of reference ranges.

Diseases/conditions related to the Uric acid test

  • Gout
  • Arthritis
  • Multiple Myeloma
  • Gout
  • Chronic Renal disease and renal failure
  • Alcoholism
  • Dehydration
  • Leukemia and lymphoma
  • Starvation
  • Metabolic acidosis
  • Toxemia of pregnancy
  • Infectious mononucleosis
  • Hyperlipidemia
  • Hemolytic anemia
  • Excessive cell destruction associated with chemotherapy and radiation treatment

Other tests related to the Uric acid test
Synovial fluid analysis

 


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Uric Acid (Serum)

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