Clinical definition of the TB-PCR test
The TB-PCR is one of the tests which may be used to confirm an infection of Tuberculosis. Tuberculosis is a disease caused by the bacteria Mycobacterium tuberculosis which usually attacks the lungs but can also affect other parts of the body. It may cause pulmonary tuberculosis and other infections such as those of the skin and abdomen. It is spread through the air when people who have the disease cough, sneeze, or spit.
The other widely used tests used in the diagnosis & screening of Tuberculosis infection are:

  • AFB, smear examination
  • Culture, Mycobacterium Tuberculosis
  • Mycobacterium antibody panel (TB-IgG, IgM, IgA)
  • Quantiferon TB Gold
  • Mantoux Test

Why is the TB-PCR test done?
The TB-PCR test is used to distinguish M. tuberculosis from other Mycobacteria.

What are the common signs/symptoms when the TB-PCR test is done?
These symptoms may be diagnosed by and screened for:

  • Unexplained weight loss
  • Fatigue
  • Fever
  • Night sweats
  • Chills
  • Loss of appetite
  • Prolonged and Persistent cough
  • Blood in sputum
  • Painful breathing
  • Painful coughing

When TB severely spreads in the lungs it shows the following symptoms include 

  • Chest pain
  • Coughing up blood
  • Prolonged cough for more than three weeks

What should I do before the TB-PCR test?

Specimen type

Specimen collection procedure

Preparatory instructions before the test *

Serum (Blood Sample)

Venipuncture - Collection of blood from a vein, usually from the arm.

No Fasting Required.

No other special preparations required.

*Subjects suffering from any illness or on oral or injectable medications are advised to consult their physician prior to requesting any tests or procedures.

How do I interpret my TB-PCR test results?

Reference Range*



No infection

‘*A Reference range is a set of values which helps the healthcare professional to interpret a medical test. It may vary with age, gender, and other factors. Reference ranges may also vary between labs, in value & units depending on instruments used and method of establishment of reference ranges’

Diseases/conditions related to the TB-PCR test

  • Tuberculosis

Other tests related to the TB-PCR test

  • Acid Fast Baciili Culture Test
  • Mantoux Test
  • Anti TB
  • Quantiferon TB Gold Test
  • Chest radiograph
  • Sputum smear
  • Molecular testing, diagnostic
  • Mycobacteria culture
  • Atypical mycobacterial infection
  • TB skin test

Synonyms : MTB by RT PCR